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Opthea Unveils Sozinibercept’s Promise to Revolutionize Wet AMD Treatment

7:03pm on Monday 2nd of June, 2025 AEST Pharmaceuticals
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Opthea Unveils Sozinibercept’s Promise to Revolutionize Wet AMD Treatment

7:03pm on Monday 2nd of June, 2025 AEST
Key Points
  • Sozinibercept targets VEGF-C/D pathways, complementing existing anti-VEGF-A therapies
  • Phase 3 trials COAST and ShORe enrolled nearly 2,000 patients globally with topline data expected mid-2025
  • Potential FDA Biologics License Application (BLA) submission in first half of 2026 with fast track and priority review prospects
  • U.S. wet AMD market valued at approximately $7 billion with over 1.2 million treated eyes annually
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