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Alterity’s ATH434 Slows Multiple System Atrophy Progression with Strong Phase 2 Data

6:45pm on Sunday 1st of June, 2025 AEST Healthcare
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Alterity’s ATH434 Slows Multiple System Atrophy Progression with Strong Phase 2 Data

6:45pm on Sunday 1st of June, 2025 AEST
Key Points
  • ATH434 achieved statistically significant slowing of disease progression on UMSARS I scale
  • Reduction and stabilization of brain iron concentrations confirmed by MRI biomarkers
  • Maintained brain volume compared to placebo over 12 months
  • Favorable safety profile with no drug-related serious adverse events
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