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How Immutep’s Eftilagimod Alfa Dose Unlocks New Hope in Breast Cancer
9:36am on Tuesday 2nd of December, 2025 AEDT
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Healthcare
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How Immutep’s Eftilagimod Alfa Dose Unlocks New Hope in Breast Cancer
9:36am on Tuesday 2nd of December, 2025 AEDT
Key Points
Phase II AIPAC-003 trial shows strong response rates in heavily pretreated metastatic breast cancer
30 mg eftilagimod alfa selected as optimal biological dose following FDA Project Optimus guidelines
Combination therapy with paclitaxel activates immune biomarkers including lymphocyte count and interferon-gamma
Higher 90 mg dose linked to increased toxicity and injection site reactions
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