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How Immutep’s Eftilagimod Alfa Dose Unlocks New Hope in Breast Cancer

9:36am on Tuesday 2nd of December, 2025 AEDT Healthcare
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How Immutep’s Eftilagimod Alfa Dose Unlocks New Hope in Breast Cancer

9:36am on Tuesday 2nd of December, 2025 AEDT
Key Points
  • Phase II AIPAC-003 trial shows strong response rates in heavily pretreated metastatic breast cancer
  • 30 mg eftilagimod alfa selected as optimal biological dose following FDA Project Optimus guidelines
  • Combination therapy with paclitaxel activates immune biomarkers including lymphocyte count and interferon-gamma
  • Higher 90 mg dose linked to increased toxicity and injection site reactions
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