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How Arovella’s Armoured CAR-iNKT Cells Could Transform Pancreatic and Gastric Cancer Treatment
10:12am on Wednesday 1st of April, 2026 AEDT
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Biotechnology
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How Arovella’s Armoured CAR-iNKT Cells Could Transform Pancreatic and Gastric Cancer Treatment
10:12am on Wednesday 1st of April, 2026 AEDT
Key Points
CLDN18.2 CAR-iNKT cells effectively kill pancreatic and gastric cancer cells in vitro
IL-12-TM armouring boosts CAR-iNKT cell expansion and tumour control
Armoured CAR-iNKT cells maintain high cytotoxicity over four serial tumour challenges
Data supports advancing to in vivo mouse models for solid tumour testing
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