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Opthea Board Shaken as Four Directors Resign Amid Trial Setbacks

Opthea Limited faces a pivotal moment as four board members resign following disappointing Phase 3 trial results and a major workforce reduction. The company’s future hinges on ongoing funding negotiations amid trading suspensions.
Ada Torres
2 June 2025

Opthea Halts Wet AMD Trials After Phase III Setbacks, Cuts Staff by 65%

Opthea Limited has discontinued its wet AMD development program following Phase III trial failures, slashing its workforce by 65% amid ongoing financial uncertainty and negotiations with investors.
Ada Torres
30 Apr 2025

Opthea Marks Milestone with Final COAST Trial Visit Ahead of Q2 Topline Data

Opthea has completed the final patient visit in its pivotal COAST Phase 3 trial evaluating sozinibercept combined with aflibercept for wet AMD, with topline results expected early Q2 2025.
Ada Torres
18 Feb 2025

Opthea Advances Sozinibercept Trials with $131.9M Cash Buffer and R&D Boost

Opthea Limited reports steady progress in its Phase 3 trials for sozinibercept, a novel treatment for wet AMD, supported by a strong cash position and a recent R&D tax incentive.
Victor Sage
31 Jan 2025

Opthea Unveils Sozinibercept’s Promise to Revolutionize Wet AMD Treatment

Opthea Limited has spotlighted Sozinibercept as a potential game-changer in wet age-related macular degeneration (AMD) therapy, presenting compelling clinical data and a clear path to U.S. market entry.
Victor Sage
29 Jan 2025